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Cellosaurus A2780/ACR6 (CVCL_D156)

[Text version]
Cell line name A2780/ACR6
Synonyms ACR6
Accession CVCL_D156
Resource Identification Initiative To cite this cell line use: A2780/ACR6 (RRID:CVCL_D156)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=12726863; DOI=10.1016/S1535-6108(03)00058-8
Sherman-Baust C.A., Weeraratna A.T., Rangel L.B.A., Pizer E.S., Cho K.R., Schwartz D.R., Shock T., Morin P.J.
Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells.
Cancer Cell 3:377-386(2003)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D156
Encyclopedic resources Wikidata; Q54606586
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number16