Cellosaurus cell line YBLi006-A (CVCL

Cellosaurus YBLi006-A (CVCL_D0QA)

Cross-references
Cell line name	YBLi006-A
Synonyms	YBL/PH/2022/0025
Accession	CVCL_D0QA
Resource Identification Initiative	To cite this cell line use: YBLi006-A (RRID:CVCL_D0QA)
Comments	From: Yashraj Biotechnology Ltd; Navi Mumbai; India. Population: Indian. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Pro871Leu (c.2612C>T); ClinVar=VCV000041812; Zygosity=Heterozygous (PubMed=37290137). Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Glu1038Gly (c.3113A>G); ClinVar=VCV000041815; Zygosity=Heterozygous (PubMed=37290137). Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Lys1183Arg (c.3548A>G); dbSNP=rs16942; Zygosity=Heterozygous (PubMed=37290137). Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Ser1613Gly (c.4837A>G); ClinVar=VCV000041827; Zygosity=Heterozygous (PubMed=37290137). Mutation; HGNC; HGNC:25568; FANCI; Simple; p.Gly27Val (c.80G>T); Zygosity=Heterozygous (PubMed=37290137). Mutation; HGNC; HGNC:25568; FANCI; Simple; p.Ala86Val (c.257C>T); ClinVar=VCV000257484; Zygosity=Heterozygous (PubMed=37290137). Mutation; HGNC; HGNC:25568; FANCI; Simple; p.Cys742Ser (c.2225G>C); ClinVar=VCV000257482; Zygosity=Heterozygous (PubMed=37290137).
Disease	BRCA1-associated hereditary breast and ovarian cancer syndrome (NCIt: C36100) Hereditary breast cancer (ORDO: Orphanet_227535)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	49Y
Category	Induced pluripotent stem cell
Publications	PubMed=37290137; DOI=10.1016/j.scr.2023.103128 Chitrangi S., Vaity P., Jamdar A., Sarkar J., Bhatt S. Derivation of breast cancer patient derived human induced pluripotent stem cell line (YBLi006-A) with FANC-BRCA gene mutations: a resource for precision & personalized medicine. Stem Cell Res. 70:103128-103128(2023)
Cell line databases/resources	hPSCreg; YBLi006-A
Biological sample resources	BioSamples; SAMEA112910788
Encyclopedic resources	Wikidata; Q123033952
Entry history
Entry creation	05-Oct-2023
Last entry update	19-Dec-2024
Version number	3