Cellosaurus logo
expasy logo

Cellosaurus MLUi007-J (CVCL_D0IJ)

[Text version]
Cell line name MLUi007-J
Accession CVCL_D0IJ
Resource Identification Initiative To cite this cell line use: MLUi007-J (RRID:CVCL_D0IJ)
Comments From: Medical Faculty, Martin Luther University Halle-Wittenberg; Halle; Germany.
Population: Caucasian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:613; APOE; Simple; p.Cys130Arg (c.388T>C); ClinVar=VCV000017864; Zygosity=Homozygous; Note=ApoE4 allele (PubMed=37001364).
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D0IA ! MLUi007-A
CVCL_D0IB ! MLUi007-B
CVCL_D0IC ! MLUi007-C
CVCL_D0ID ! MLUi007-D
CVCL_D0IE ! MLUi007-E
CVCL_D0IF ! MLUi007-F
CVCL_D0IG ! MLUi007-G
CVCL_D0IH ! MLUi007-H
CVCL_D0II ! MLUi007-I
Sex of cell Female
Age at sampling 64Y
Category Induced pluripotent stem cell
Publications

PubMed=37001364; DOI=10.1016/j.scr.2023.103072
Jung M., Hartmann C., Ehrhardt T., Peter L.-M., Abid C.L., Harwardt B., Hirschfeld J., Claus C., Haferkamp U., Pless O., Nastainczyk-Wulf M., Kehlen A., Schlote D., Schroder I.S., Rujescu D.
Generation of a set of induced pluripotent stem cell lines from two Alzheimer disease patients carrying APOE4 (MLUi007-J; MLUi008-A) and healthy old donors carrying APOE3 (MLUi009-A; MLUi010-B) to study APOE in aging and disease.
Stem Cell Res. 69:103072-103072(2023)

PubMed=38612385; DOI=10.3390/ijms25073575; PMCID=PMC11011287
Xavier G., Navarrete Santos A., Hartmann C., Santoro M.L., Flegel N., Reinsch J., Majer A., Ehrhardt T., Pfeifer J., Simm A., Hollemann T., Belangero S.I., Rujescu D., Jung M.
Comparison of extracellular vesicles from induced pluripotent stem cell-derived brain cells.
Int. J. Mol. Sci. 25:3575.1-3575.13(2024)

Cross-references
Cell line databases/resources hPSCreg; MLUi007-J
Biological sample resources BioSamples; SAMEA112748717
Encyclopedic resources Wikidata; Q123033072
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number3