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Cellosaurus M24 (CVCL_D032)

[Text version]
Cell line name M24
Synonyms UCLA-SO-M24; UCLA-SO-24
Accession CVCL_D032
Resource Identification Initiative To cite this cell line use: M24 (RRID:CVCL_D032)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12270.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23851445).
HLA typing Source: PubMed=15592718
Class I
HLA-AA*02:01,68:01:01
HLA-BB*40:01:01,40:02
HLA-CC*03:04,02:02:02
Class II
HLA-DPDPB1*04:01
HLA-DQDQB1*03:01:01,05:02
HLA-DRDRB1*04:01:01,16:02
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_3915 (M24met)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB

Markers:
AmelogeninX,Y
CSF1PO12
D3S135814,16
D5S81813
D7S8209
D13S3178,11
FGA18,19
TH016
TPOX8,11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=2009538
Mueller B.M., Romerdahl C.A., Trent J.M., Reisfeld R.A.
Suppression of spontaneous melanoma metastasis in scid mice with an antibody to the epidermal growth factor receptor.
Cancer Res. 51:2193-2198(1991)

Patent=US5840317
Morton D.L.
Composition comprising tumor cell lines containing GD2 ganglioside GM2 ganglioside, M-TAA, and either M-urinary antigen or M-fetal antigen.
Patent number US5840317, 24-Nov-1998

Patent=US5993828
Morton D.L.
Tumor associated antigen compositions and methods.
Patent number US5993828, 30-Nov-1999

PubMed=15592718; DOI=10.1007/s00262-004-0561-5
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello F., Dodi I.A., Lopez Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line collections (Providers) ATCC; CRL-12270
Cell line databases/resources cancercelllines; CVCL_D032
ESTDAB; ESTDAB-043
ESTDAB; ESTDAB-134
Encyclopedic resources Wikidata; Q54903558
Polymorphism and mutation databases Cosmic; 2163789
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number16