Cell line name |
M24 |
Synonyms |
UCLA-SO-M24; UCLA-SO-24 |
Accession |
CVCL_D032 |
Resource Identification Initiative |
To cite this cell line use: M24 (RRID:CVCL_D032) |
Comments |
Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12270. Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027. |
Sequence variations |
- Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23851445).
|
HLA typing |
Source: PubMed=15592718
Class I | HLA-A | A*02:01,68:01:01 | HLA-B | B*40:01:01,40:02 | HLA-C | C*03:04,02:02:02 | Class II | HLA-DP | DPB1*04:01 | HLA-DQ | DQB1*03:01:01,05:02 | HLA-DR | DRB1*04:01:01,16:02 |
|
Disease |
Amelanotic melanoma (NCIt: C3802) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Children:
|
Sex of cell |
Male |
Age at sampling |
Age unspecified |
Category |
Cancer cell line |
STR profile |
Source(s): ESTDAB
Markers: Run an STR similarity search on this cell line |
Publications | PubMed=2009538 Mueller B.M., Romerdahl C.A., Trent J.M., Reisfeld R.A. Suppression of spontaneous melanoma metastasis in scid mice with an antibody to the epidermal growth factor receptor. Cancer Res. 51:2193-2198(1991) Patent=US5840317 Morton D.L. Composition comprising tumor cell lines containing GD2 ganglioside GM2 ganglioside, M-TAA, and either M-urinary antigen or M-fetal antigen. Patent number US5840317, 24-Nov-1998 Patent=US5993828 Morton D.L. Tumor associated antigen compositions and methods. Patent number US5993828, 30-Nov-1999 PubMed=15592718; DOI=10.1007/s00262-004-0561-5 Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello F., Dodi I.A., Lopez Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F. High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity. Cancer Immunol. Immunother. 54:141-148(2005) PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006 Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P. Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling. Mol. Cancer Res. 11:1166-1178(2013) |
Cross-references |
Cell line collections (Providers) |
ATCC; CRL-12270
|
Cell line databases/resources |
cancercelllines; CVCL_D032
ESTDAB; ESTDAB-043
ESTDAB; ESTDAB-134
|
Encyclopedic resources |
Wikidata; Q54903558
|
Polymorphism and mutation databases |
Cosmic; 2163789
|
Entry history |
Entry creation | 22-Oct-2012 |
Last entry update | 05-Oct-2023 |
Version number | 16 |
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