ID   N/TERT-1
AC   CVCL_CW92
SY   N/Tert-1; N/TERT 1; N/TERT1; NTERT-1; NTert-1; NTert1
DR   Wikidata; Q54907285
RX   PubMed=10648628;
RX   PubMed=28928444;
WW   https://dermatology.bwh.harvard.edu/docs/Cell-Culture-Core-Cell-Lines.pdf
CC   Karyotypic information: 47,XY,+20 (PubMed=28928444).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_UZ57 ! N
SX   Male
AG   <1M
CA   Telomerase immortalized cell line
DT   Created: 13-07-16; Last updated: 19-12-24; Version: 13
//
RX   PubMed=10648628; DOI=10.1128/mcb.20.4.1436-1447.2000; PMCID=PMC85304;
RA   Dickson M.A., Hahn W.C., Ino Y., Ronfard V., Wu J.Y., Weinberg R.A.,
RA   Louis D.N., Li F.P., Rheinwald J.G.;
RT   "Human keratinocytes that express hTERT and also bypass a
RT   p16(INK4a)-enforced mechanism that limits life span become immortal yet
RT   retain normal growth and differentiation characteristics.";
RL   Mol. Cell. Biol. 20:1436-1447(2000).
//
RX   PubMed=28928444; DOI=10.1038/s41598-017-12041-y; PMCID=PMC5605545;
RA   Smits J.P.H., Niehues H., Rikken G., van Vlijmen-Willems I.M.J.J.,
RA   van de Zande G.W.H.J.F., Zeeuwen P.L.J.M., Schalkwijk J.,
RA   van den Bogaard E.H.J.;
RT   "Immortalized N/TERT keratinocytes as an alternative cell source in 3D
RT   human epidermal models.";
RL   Sci. Rep. 7:11838-11838(2017).
//