Cellosaurus cell line OCUP-A1 (CVCL

Cellosaurus OCUP-A1 (CVCL_CW20)

Cross-references
Cell line name	OCUP-A1
Synonyms	Osaka City University Pancreas-A1
Accession	CVCL_CW20
Resource Identification Initiative	To cite this cell line use: OCUP-A1 (RRID:CVCL_CW20)
Comments	Population: Japanese. Doubling time: 20.6 +- 1.2 hours (PubMed=27067801). Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations	Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (PubMed=27067801). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (PubMed=27067801). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg209Lysfs*6 (c.626_627delGA); ClinVar=VCV000372539; Zygosity=Heterozygous (PubMed=27067801).
Disease	Pancreatic undifferentiated carcinoma (NCIt: C5722)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	60-70Y
Category	Cancer cell line
Publications	PubMed=27067801; DOI=10.1186/s12885-016-2297-y; PMCID=PMC4828819 Miura K., Kimura K., Amano R., Yamazoe S., Ohira G., Murata A., Nishio K., Hasegawa T., Yashiro M., Nakata B., Ohira M., Hirakawa K. Establishment and characterization of new cell lines of anaplastic pancreatic cancer, which is a rare malignancy: OCUP-A1 and OCUP-A2. BMC Cancer 16:268.1-268.13(2016)
Cell line databases/resources	cancercelllines; CVCL_CW20
Encyclopedic resources	Wikidata; Q54931843
Polymorphism and mutation databases	Cosmic; 2795399
Entry history
Entry creation	13-Jul-2016
Last entry update	19-Dec-2024
Version number	11