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Cellosaurus FS 6 (CVCL_CW15)

[Text version]
Cell line name FS 6
Synonyms FS6
Accession CVCL_CW15
Resource Identification Initiative To cite this cell line use: FS 6 (RRID:CVCL_CW15)
Comments Characteristics: Provides a powerful and convenient model for assaying potential tumor promoters and for testing potential antitumor and antiproliferative agents that might act on the v-Ha-ras pathways (ATCC=CRL-3099).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P01115; Harvey murine sarcoma virus H-Ras (V-Ha-ras).
Transformant: Activated HRAS.
Disease Mouse fibrosarcoma (NCIt: C24017)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c F1 Tg.AC transgenic.
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=17952114; DOI=10.1038/sj.onc.1210866
Leder A., McMenamin J., Zhou F., Moran J.L., Beier D.R., Leder P.
Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency.
Oncogene 27:2456-2465(2008)

Cross-references
Cell line collections (Providers) ATCC; CRL-3099
Encyclopedic resources Wikidata; Q54835183
Entry history
Entry creation13-Jul-2016
Last entry update19-Dec-2024
Version number7