ID   IMSUTi002-A-2
AC   CVCL_C9HE
SY   7F3955-KMT2A-AFF1; CRIEPIi003-A-2
DR   hPSCreg; IMSUTi002-A-2
DR   Wikidata; Q123032699
RX   PubMed=37639801;
CC   From: Sustainable System Research Laboratory, Central Research Institute of Electric Power Industry (CRIEPI); Chiba; Japan.
CC   Population: Japanese.
CC   Characteristics: Transfected with a Tet-on system so as to induce the expression of EGFP and the KMT2A-AFF1 fusion protein with the addition of doxycycline to the culture medium (PubMed=37639801).
CC   Transfected with: HGNC; 7135; AFF1 (KMT2-AFF1/MLL-AF4 fusion).
CC   Transfected with: HGNC; 7132; KMT2A (KMT2-AFF1/MLL-AF4 fusion).
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
CC   Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_XI76 ! IMSUTi002-A
SX   Male
AG   Age unspecified
CA   Induced pluripotent stem cell
DT   Created: 05-10-23; Last updated: 30-01-24; Version: 2
//
RX   PubMed=37639801; DOI=10.1016/j.scr.2023.103185;
RA   Takahashi M.;
RT   "Generation of a human induced pluripotent stem cell line harboring
RT   the infant leukemia-associated fusion gene, KMT2A-AFF1
RT   (IMSUTi002-A-2).";
RL   Stem Cell Res. 71:103185-103185(2023).
//