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Cellosaurus 7G2.2 (CVCL_C9FV)

[Text version]
Cell line name 7G2.2
Accession CVCL_C9FV
Resource Identification Initiative To cite this cell line use: 7G2.2 (RRID:CVCL_C9FV)
Comments Doubling time: 13 hours (PubMed=9631008).
Monoclonal antibody isotype: IgG1, kappa.
Monoclonal antibody target: UniProtKB; P01730; Human CD4.
Miscellaneous: As the immunized splenic B-cells are from humanized transgenic HC2/KCo5/JHD/JCkappaD mice the produced mAB is of human origin.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_4032 (P3X63Ag8.653)
Category Hybridoma
Publications

PubMed=9631008; DOI=10.1038/nbt0796-845
Fishwild D.M., O'Donnell S.L., Bengoechea T., Hudson D.V., Harding F., Bernhard S.L., Jones D., Kay R.M., Higgins K.M., Schramm S.R., Lonberg N.
High-avidity human IgG kappa monoclonal antibodies from a novel strain of minilocus transgenic mice.
Nat. Biotechnol. 14:845-851(1996)

Patent=US8231877
Lonberg N., Kay R.M., Fishwild D.M.
Heterologous antibodies which bind human CD4.
Patent number US8231877, 31-Jul-2012

Cross-references
Encyclopedic resources Wikidata; Q123030326
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2