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Cellosaurus SH-SY5Y/Cas9-hyg (CVCL_C9F2)

[Text version]
Cell line name SH-SY5Y/Cas9-hyg
Accession CVCL_C9F2
Resource Identification Initiative To cite this cell line use: SH-SY5Y/Cas9-hyg (RRID:CVCL_C9F2)
Comments Population: Caucasian.
Characteristics: Stably expresses a EF1a-Cas9-HA-SV40-EGFP-IRES-HygR construct (GeneCopoeia=SL550).
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0019 (SH-SY5Y)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) GeneCopoeia; SL550
Encyclopedic resources Wikidata; Q123033480
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number4