Cellosaurus cell line GSC-0131 (CVCL

Cellosaurus GSC-0131 (CVCL_C9EE)

Cross-references
Cell line name	GSC-0131
Synonyms	GSC0131; 0131
Accession	CVCL_C9EE
Resource Identification Initiative	To cite this cell line use: GSC-0131 (RRID:CVCL_C9EE)
Comments	Group: Cancer stem cell line. Omics: CRISPR phenotypic screen. Omics: Deep exome analysis. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val147Asp (c.440T>A); ClinVar=VCV001351017; Zygosity=Homozygous (PubMed=26673326).
Disease	Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Adult
Category	Cancer cell line
Publications	PubMed=19427293; DOI=10.1016/j.stem.2009.03.003; PMCID=PMC7227614 Son M.J., Woolard K.D., Nam D.-H., Lee J., Fine H.A. SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 4:440-452(2009) PubMed=26673326; DOI=10.1016/j.celrep.2015.11.021; PMCID=PMC4691575 Toledo C.M., Ding Y., Hoellerbauer P., Davis R.J., Basom R., Girard E.J., Lee E., Corrin P., Hart T., Bolouri H., Davison J., Zhang Q., Hardcastle J., Aronow B.J., Plaisier C.L., Baliga N.S., Moffat J., Lin Q., Li X.-N., Nam D.-H., Lee J., Pollard S.M., Zhu J., Delrow J.J., Clurman B.E., Olson J.M., Paddison P.J. Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in glioblastoma stem-like cells. Cell Rep. 13:2425-2439(2015)
CRISP screens repositories	BioGRID_ORCS_Cell_line; 297
Encyclopedic resources	Wikidata; Q123031372
Gene expression databases	GEO; GSM1715941 GEO; GSM1715942 GEO; GSM1715943 GEO; GSM1715944
Entry history
Entry creation	05-Oct-2023
Last entry update	19-Dec-2024
Version number	3