Cellosaurus cell line SNU-16/Cas9-hyg (CVCL

Cross-references
Cell line name	SNU-16/Cas9-hyg
Accession	CVCL_C9DM
Resource Identification Initiative	To cite this cell line use: SNU-16/Cas9-hyg (RRID:CVCL_C9DM)
Comments	Population: Korean. Characteristics: Stably expresses a EF1a-Cas9-HA-SV40-EGFP-IRES-HygR construct (GeneCopoeia=SL545). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9. Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations	Gene fusion; HGNC; 1681; CD44 + HGNC; 10940; SLC1A2; Name(s)=CD44-SLC1A2 (from parent cell line). Mutation; HGNC; 7329; MSH6; Simple; p.Lys1358fs*2 (c.4065_4066insTTGA); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Tyr205Phe (c.614A>T); ClinVar=VCV000376682; Zygosity=Homozygous (from parent cell line).
Disease	Gastric adenocarcinoma (NCIt: C4004)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0076 (SNU-16)
Sex of cell	Female
Age at sampling	33Y
Category	Cancer cell line
Cell line collections (Providers)	GeneCopoeia; SL545
Encyclopedic resources	Wikidata; Q123033539
Entry history
Entry creation	05-Oct-2023
Last entry update	10-Sep-2024
Version number	3