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Cellosaurus SNU-423/Cas9-hyg (CVCL_C9DG)

[Text version]
Cell line name SNU-423/Cas9-hyg
Accession CVCL_C9DG
Resource Identification Initiative To cite this cell line use: SNU-423/Cas9-hyg (RRID:CVCL_C9DG)
Comments Population: Korean.
Characteristics: Stably expresses a EF1a-Cas9-HA-SV40-EGFP-IRES-HygR construct (GeneCopoeia=SL538).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; c.376-2A>G; ClinVar=VCV000186236; Zygosity=Unspecified; Note=Splice acceptor mutation (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0366 (SNU-423)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) GeneCopoeia; SL538
Encyclopedic resources Wikidata; Q123033542
Entry history
Entry creation05-Oct-2023
Last entry update10-Sep-2024
Version number4