Cellosaurus cell line NCI-H1650-GAS-Luc2 (CVCL

Cellosaurus NCI-H1650-GAS-Luc2 (CVCL_C9CY)

[Text version]

Cell line name

NCI-H1650-GAS-Luc2

Accession

CVCL_C9CY

Resource Identification Initiative

To cite this cell line use: NCI-H1650-GAS-Luc2 (RRID:CVCL_C9CY)

Comments

Population: Caucasian.
Characteristics: Stably expresses firefly luciferase under the control of the gamma-activated site (GAS) promoter (ATCC=CRL-5883-GAS-LUC2).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.

Sequence variations

Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; c.673-2A>G (IVS6-2A>G); ClinVar=VCV000458555; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).

Disease

Minimally invasive lung adenocarcinoma (NCIt: C2923)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_1483 (NCI-H1650)

Sex of cell

Male

Age at sampling

27Y

Category

Cancer cell line

STR profile

Source(s): ATCC=CRL-5883-GAS-LUC2

Markers:

Amelogenin	X
CSF1PO	11
D5S818	11
D7S820	8,9
D13S317	11
D16S539	11,12
TH01	9.3
TPOX	11
vWA	18

Cross-references

Cell line collections (Providers)

ATCC; CRL-5883-GAS-LUC2

Encyclopedic resources

Wikidata; Q123033156

Entry history

Entry creation

05-Oct-2023

Last entry update

19-Dec-2024

Version number