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Cellosaurus HCC827-GAS-Luc2 (CVCL_C9CW)

[Text version]
Cell line name HCC827-GAS-Luc2
Accession CVCL_C9CW
Resource Identification Initiative To cite this cell line use: HCC827-GAS-Luc2 (RRID:CVCL_C9CW)
Comments Population: Caucasian.
Characteristics: Stably expresses firefly luciferase under the control of the gamma-activated site (GAS) promoter (ATCC=CRL-2868-GAS-LUC2).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2236_2250del15); ClinVar=VCV000177620; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Val218del (c.646_648GTG[2]) (c.652_654delGTG); ClinVar=VCV000634761; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2063 (HCC827)
Sex of cell Female
Age at sampling 39Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2868-GAS-LUC2

Markers:
AmelogeninX
CSF1PO11
D5S81812
D7S82011,12
D13S3179
D16S53912
TH016
TPOX8
vWA18

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Cross-references
Cell line collections (Providers) ATCC; CRL-2868-GAS-LUC2
Encyclopedic resources Wikidata; Q123031558
Entry history
Entry creation05-Oct-2023
Last entry update10-Sep-2024
Version number4