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Cellosaurus PER-909 (CVCL_C9CN)

[Text version]
Cell line name PER-909
Synonyms P896-CL
Accession CVCL_C9CN
Resource Identification Initiative To cite this cell line use: PER-909 (RRID:CVCL_C9CN)
Comments Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Nose, nasal cavity; UBERON=UBERON_0001707.
Sequence variations
  • Gene fusion; HGNC; HGNC:13575; BRD4 + HGNC; HGNC:29919; NUTM1; Name(s)=BRD4-NUTM1, BRD4-NUT; Note=BRD4 exon 15 fused to NUTM1 exon 2 (PubMed=26551281).
Disease NUT carcinoma (NCIt: C45716)
NUT midline carcinoma (ORDO: Orphanet_443167)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C9CP ! PER-904N
Sex of cell Female
Age at sampling 14Y
Category Cancer cell line
Publications

PubMed=26551281; DOI=10.1038/oncsis.2015.33; PMCID=PMC4670959
Stirnweiss A., McCarthy K., Oommen J., Crook M.L., Hardy K., Kees U.R., Wilton S.D., Anazodo A.C., Beesley A.H.
A novel BRD4-NUT fusion in an undifferentiated sinonasal tumor highlights alternative splicing as a contributing oncogenic factor in NUT midline carcinoma.
Oncogenesis 4:e174.1-e174.5(2015)

PubMed=29348827; DOI=10.18632/oncotarget.22862; PMCID=PMC5762512
Stirnweiss A., Oommen J., Kotecha R.S., Kees U.R., Beesley A.H.
Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-an aggressive and fatal disease.
Oncotarget 8:112313-112329(2017)

Cross-references
Encyclopedic resources Wikidata; Q123033267
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number3