Cellosaurus cell line 14169 (CVCL

Cross-references
Cell line name	14169
Accession	CVCL_C9CL
Resource Identification Initiative	To cite this cell line use: 14169 (RRID:CVCL_C9CL)
Comments	Omics: Deep exome analysis. Omics: Transcriptome analysis by RNAseq.
Sequence variations	Gene fusion; HGNC; HGNC:13575; BRD4 + HGNC; HGNC:29919; NUTM1; Name(s)=BRD4-NUTM1, BRD4-NUT; Note=BRD4 exon 15 fused to NUTM1 exon 2 (PubMed=24736545).
Disease	NUT carcinoma (NCIt: C45716) NUT midline carcinoma (ORDO: Orphanet_443167)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=24736545; DOI=10.1158/0008-5472.CAN-13-2658; PMCID=PMC4097982 Wang R.-R., Liu W., Helfer C.M., Bradner J.E., Hornick J.L., Janicki S.M., French C.A., You J.-X. Activation of SOX2 expression by BRD4-NUT oncogenic fusion drives neoplastic transformation in NUT midline carcinoma. Cancer Res. 74:3332-3343(2014) PubMed=29348827; DOI=10.18632/oncotarget.22862; PMCID=PMC5762512 Stirnweiss A., Oommen J., Kotecha R.S., Kees U.R., Beesley A.H. Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-an aggressive and fatal disease. Oncotarget 8:112313-112329(2017)
Encyclopedic resources	Wikidata; Q123030221
Entry history
Entry creation	05-Oct-2023
Last entry update	19-Dec-2024
Version number	3