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Cellosaurus NCI-H1437/Cas9-hyg (CVCL_C9BM)

[Text version]
Cell line name NCI-H1437/Cas9-hyg
Accession CVCL_C9BM
Resource Identification Initiative To cite this cell line use: NCI-H1437/Cas9-hyg (RRID:CVCL_C9BM)
Comments Population: Caucasian.
Characteristics: Stably expresses a EF1a-Cas9-HA-SV40-EGFP-IRES-HygR construct (GeneCopoeia=SL536).
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg267Pro (c.800G>C); ClinVar=VCV000428867; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1472 (NCI-H1437)
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) GeneCopoeia; SL536
Encyclopedic resources Wikidata; Q123033154
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number4