ID   NCI-H1299/Cas9 AAVS1
AC   CVCL_C9BI
SY   NCI-H1299-Cas9 AAVS1
DR   GeneCopoeia; SL501
DR   Wikidata; Q123033152
CC   Population: Caucasian.
CC   Characteristics: Stably expresses a CMV-3xFLAG-Cas9-NLS-bGHPolyA-EF1a-copGFP-T2A-PuroR-SV40pa construct from the AAVS1 safe locus (GeneCopoeia=SL501).
CC   Karyotypic information: Has lost chromosome Y (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
CC   Transfected with: UniProtKB; Q6WV12; Pontellina plumata GFP2 (copGFP).
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
DI   NCIt; C4450; Lung large cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0060 ! NCI-H1299
SX   Male
AG   43Y
CA   Cancer cell line
DT   Created: 05-10-23; Last updated: 30-01-24; Version: 2
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