Cellosaurus HEK293T/ACE2 (CVCL_C9BE)
Cell line name | HEK293T/ACE2 |
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Synonyms | HEK293T-hACE2 |
Accession | CVCL_C9BE |
Resource Identification Initiative | To cite this cell line use: HEK293T/ACE2 (RRID:CVCL_C9BE) |
Comments | Group: SARS-CoV-2 research cell line. Characteristics: Expresses ACE2 under the control of the CMV promoter (GeneCopoeia=SL221). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:13557; ACE2. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA). Omics: CRISPR phenotypic screen. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0063 (HEK293T) |
Sex of cell | Female |
Age at sampling | Fetus |
Category | Transformed cell line |
Publications | PubMed=35086559; DOI=10.1186/s13073-022-01013-1; PMCID=PMC8792531 |
Cross-references | |
Cell line collections (Providers) | GeneCopoeia; SL221 |
CRISP screens repositories | BioGRID_ORCS_Cell_line; 1668 |
Encyclopedic resources | Wikidata; Q123031593 |
Entry history | |
Entry creation | 05-Oct-2023 |
Last entry update | 19-Dec-2024 |
Version number | 4 |