Cellosaurus HEK293T/ACE2 (CVCL_C9BE)
| Cell line name | HEK293T/ACE2 |
|---|---|
| Synonyms | HEK293T-hACE2 |
| Accession | CVCL_C9BE |
| Resource Identification Initiative | To cite this cell line use: HEK293T/ACE2 (RRID:CVCL_C9BE) |
| Comments | Group: SARS-CoV-2 research cell line. Characteristics: Expresses ACE2 under the control of the CMV promoter (GeneCopoeia=SL221). Genetic integration: Method=Transfection/transduction; Gene=HGNC; 13557; ACE2. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA). Omics: CRISPR phenotypic screen. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0063 (HEK293T) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Publications | PubMed=35086559; DOI=10.1186/s13073-022-01013-1; PMCID=PMC8792531 |
| Cross-references | |
| Cell line collections (Providers) | GeneCopoeia; SL221 |
| CRISP screens repositories | BioGRID_ORCS_Cell_line; 1668 |
| Encyclopedic resources | Wikidata; Q123031593 |
| Entry history | |
| Entry creation | 05-Oct-2023 |
| Last entry update | 10-Sep-2024 |
| Version number | 3 |