Cellosaurus HeLa RelA-mNeonGreen (CVCL_C9AQ)
| Cell line name | HeLa RelA-mNeonGreen |
|---|---|
| Synonyms | HeLa p65-mNeonGreen; HeLa RelA |
| Accession | CVCL_C9AQ |
| Resource Identification Initiative | To cite this cell line use: HeLa RelA-mNeonGreen (RRID:CVCL_C9AQ) |
| Comments | Population: African American. Characteristics: Expression of Cas9 can be induced by doxocycline (from parent cell line). Characteristics: Transduced with a pR14_p65-mNeonGreen construct (PubMed=31626775). Genetic integration: Method=Transduction; Gene=HGNC; 9955; RELA. Genetic integration: Method=Transduction; Gene=FPbase; ZRKRV; mNeonGreen (Note=Derivative of Branchiostoma lanceolatum LanYFP). Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9. Genetic integration: Method=Transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Arg360del). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Omics: CRISPR phenotypic screen. Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C9AP (HeLa-TetR-Cas9) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Publications | PubMed=31626775; DOI=10.1016/j.cell.2019.09.016; PMCID=PMC6886477 |
| Cross-references | |
| CRISP screens repositories | BioGRID_ORCS_Cell_line; 1605 |
| Encyclopedic resources | Wikidata; Q123031618 |
| Entry history | |
| Entry creation | 05-Oct-2023 |
| Last entry update | 10-Sep-2024 |
| Version number | 3 |