Cellosaurus cell line PER-624 (CVCL

Cross-references
Cell line name	PER-624
Accession	CVCL_C8YW
Resource Identification Initiative	To cite this cell line use: PER-624 (RRID:CVCL_C8YW)
Comments	Omics: Deep exome analysis. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations	Gene fusion; HGNC; HGNC:13575; BRD4 + HGNC; HGNC:29919; NUTM1; Name(s)=BRD4-NUTM1, BRD4-NUT; Note=BRD4 exon 15 fused to NUTM1 exon 2 (PubMed=23128391; PubMed=29348827).
Disease	NUT carcinoma (NCIt: C45716) NUT midline carcinoma (ORDO: Orphanet_443167)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	11Y
Category	Cancer cell line
Publications	PubMed=23128391; DOI=10.1038/onc.2012.487 Thompson-Wicking K., Francis R.W., Stirnweiss A., Ferrari E., Welch M.D., Baker E., Murch A.R., Gout A.M., Carter K.W., Charles A.K., Phillips M.B., Kees U.R., Beesley A.H. Novel BRD4-NUT fusion isoforms increase the pathogenic complexity in NUT midline carcinoma. Oncogene 32:4664-4674(2013) PubMed=29348827; DOI=10.18632/oncotarget.22862; PMCID=PMC5762512 Stirnweiss A., Oommen J., Kotecha R.S., Kees U.R., Beesley A.H. Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-an aggressive and fatal disease. Oncotarget 8:112313-112329(2017)
Encyclopedic resources	Wikidata; Q123033263
Entry history
Entry creation	05-Oct-2023
Last entry update	19-Dec-2024
Version number	3