ID   A549 PPM1H-BromoTag
AC   CVCL_C8YV
SY   A549 PPM1H-BromoTag CRISPR/Cas9 knock-in
DR   Wikidata; Q123030359
RX   DOI=10.1101/2023.07.25.550405;
CC   Population: Caucasian.
CC   Characteristics: Using CRISPR/Cas9 PPM1H was tagged on both alleles at the C-terminus with a BromoTag thus enabling the rapid and selective degradation of PPM1H (DOI=10.1101/2023.07.25.550405).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 13575; BRD4 (with p.Met1_Lys332del, p.Pro461_Phe1362del and p.Leu387Ala = BromoTag).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 05-10-23; Last updated: 02-05-24; Version: 3
//
RX   DOI=10.1101/2023.07.25.550405;
RA   Phung T.K., Berndsen K., Le Cong Huyen Bao Phan T., Muqit M.M.K.,
RA   Alessi D.R., Nirujogi R.S.;
RT   "CURTAIN -- a unique Web-based tool for exploration and sharing of
RT   MS-based proteomics data.";
RL   bioRxiv 2023:07.25.550405-07.25.550405(2023).
//