• Gene fusion; HGNC; HGNC:13575; BRD4 + HGNC; HGNC:29919; NUTM1; Name(s)=BRD4-NUTM1, BRD4-NUT; Note=BRD4 exon 11 fused to NUTM1 exon 2 (PubMed=23128391; PubMed=24518598; PubMed=29348827).
  

PubMed=1785673; DOI=10.1097/00043426-199124000-00011
Kees U.R., Mulcahy M.T., Willoughby M.L.N.
Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19).
Am. J. Pediatr. Hematol. Oncol. 13:459-464(1991)

PubMed=17934517; DOI=10.1038/sj.onc.1210852
French C.A., Ramirez C.L., Kolmakova J., Hickman T.T., Cameron M.J., Thyne M.E., Kutok J.L., Toretsky J.A., Tadavarthy A.K., Kees U.R., Fletcher J.A., Aster J.C.
BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells.
Oncogene 27:2237-2242(2008)

PubMed=21447744; DOI=10.1158/0008-5472.CAN-10-3513; PMCID=PMC3070805
Schwartz B.E., Hofer M.D., Lemieux M.E., Bauer D.E., Cameron M.J., West N.H., Agoston E.S., Reynoird N., Khochbin S., Ince T.A., Christie A.L., Janeway K.A., Vargas S.O., Perez-Atayde A.R., Aster J.C., Sallan S.E., Kung A.L., Bradner J.E., French C.A.
Differentiation of NUT midline carcinoma by epigenomic reprogramming.
Cancer Res. 71:2686-2696(2011)

PubMed=23128391; DOI=10.1038/onc.2012.487
Thompson-Wicking K., Francis R.W., Stirnweiss A., Ferrari E., Welch M.D., Baker E., Murch A.R., Gout A.M., Carter K.W., Charles A.K., Phillips M.B., Kees U.R., Beesley A.H.
Novel BRD4-NUT fusion isoforms increase the pathogenic complexity in NUT midline carcinoma.
Oncogene 32:4664-4674(2013)

PubMed=24518598; DOI=10.1038/bjc.2014.54; PMCID=PMC3950881
Beesley A.H., Stirnweiss A., Ferrari E., Endersby R., Howlett M., Failes T.W., Arndt G.M., Charles A.K., Cole C.H., Kees U.R.
Comparative drug screening in NUT midline carcinoma.
Br. J. Cancer 110:1189-1198(2014)

PubMed=29348827; DOI=10.18632/oncotarget.22862; PMCID=PMC5762512
Stirnweiss A., Oommen J., Kotecha R.S., Kees U.R., Beesley A.H.
Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-an aggressive and fatal disease.
Oncotarget 8:112313-112329(2017)