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Cellosaurus HEK293T DNAJC5 KO (CVCL_C8UP)

[Text version]
Cell line name HEK293T DNAJC5 KO
Synonyms HEK293T-DNAJC5-KO
Accession CVCL_C8UP
Resource Identification Initiative To cite this cell line use: HEK293T DNAJC5 KO (RRID:CVCL_C8UP)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:16235; DNAJC5.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=36626307; DOI=10.7554/eLife.85837; PMCID=PMC9876576
Wu S.-J., Hernandez Villegas N.C., Sirkis D.W., Thomas-Wright I., Wade-Martins R., Schekman R.W.
Unconventional secretion of alpha-synuclein mediated by palmitoylated DNAJC5 oligomers.
eLife 12:e85837.1-e85837.29(2023)

Cross-references
Encyclopedic resources Wikidata; Q123031590
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number4