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Cellosaurus CUTO-18 (CVCL_C8TH)

[Text version]
Cell line name CUTO-18
Synonyms CUTO18; Colorado University Thoracic Oncology 18
Accession CVCL_C8TH
Resource Identification Initiative To cite this cell line use: CUTO-18 (RRID:CVCL_C8TH)
Sequence variations
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Ser768_Asp770dupSerValAsp (c.2303_2311dup) (S768_D770dupSVD); ClinVar=VCV000045253; Zygosity=Heterozygous (PubMed=33355298).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=33355298; DOI=10.1158/1078-0432.CCR-20-3555; PMCID=PMC7926264
Estrada-Bernal A., Le A.T., Doak A.E., Tirunagaru V.G., Silva S., Bull M.R., Smaill J.B., Patterson A.V., Kim C., Liu S.V., Doebele R.C.
Tarloxotinib is a hypoxia-activated pan-HER kinase inhibitor active against a broad range of HER-family oncogenes.
Clin. Cancer Res. 27:1463-1475(2021)

Cross-references
Encyclopedic resources Wikidata; Q123030988
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number3