Cellosaurus cell line CUTO-23 (CVCL

Cellosaurus CUTO-23 (CVCL_C8SZ)

Cross-references
Cell line name	CUTO-23
Synonyms	CUTO23; Colorado University Thoracic Oncology 23
Accession	CVCL_C8SZ
Resource Identification Initiative	To cite this cell line use: CUTO-23 (RRID:CVCL_C8SZ)
Comments	Omics: Transcriptomics; RNAseq.
Sequence variations	Gene fusion; HGNC; HGNC:1697; CD74 + HGNC; HGNC:10261; ROS1; Name(s)=CD74-ROS1 (PubMed=30538120).
Disease	Lung adenocarcinoma (NCIt: C3512)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=29636358; DOI=10.1158/1078-0432.CCR-17-2452; PMCID=PMC6050099 McCoach C.E., Le A.T., Gowan K., Jones K.L., Schubert L., Doak A.E., Estrada-Bernal A., Davies K.D., Merrick D.T., Bunn P.A. Jr., Purcell W.T., Dziadziuszko R., Varella-Garcia M., Aisner D.L., Camidge D.R., Doebele R.C. Resistance mechanisms to targeted therapies in ROS1(+) and ALK(+) non-small cell lung cancer. Clin. Cancer Res. 24:3334-3347(2018) PubMed=30538120; DOI=10.1158/0008-5472.CAN-18-1492; PMCID=PMC6359944 Neel D.S., Allegakoen D.V., Olivas V., Mayekar M.K., Hemmati G., Chatterjee N., Blakely C.M., McCoach C.E., Rotow J.K., Le A.T., Karachaliou N., Rosell R., Riess J.W., Nichols R., Doebele R.C., Bivona T.G. Differential subcellular localization regulates oncogenic signaling by ROS1 kinase fusion proteins. Cancer Res. 79:546-556(2019)
Encyclopedic resources	Wikidata; Q123030989
Gene expression databases	GEO; GSM7675355 GEO; GSM7675356 GEO; GSM7675357 GEO; GSM7675358 GEO; GSM7675359 GEO; GSM7675360
Entry history
Entry creation	05-Oct-2023
Last entry update	10-Apr-2025
Version number	5