ID   BJ-TERT/LT/ST/RASV12
AC   CVCL_C8QQ
SY   BJeLR; BJ-ELR; BJ ELR; ELR
DR   CLO; CLO_0037212
DR   EFO; EFO_0007750
DR   Wikidata; Q123030819
RX   PubMed=18355723;
CC   Population: Caucasian.
CC   Characteristics: Tumorigenic in nude mice (PubMed=18355723).
CC   Doubling time: 15 hours (PubMed=18355723).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03081; SV40 small T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
CC   Cell type: Fibroblast of foreskin; CL=CL_1001608.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C8QP ! BJ-TERT/LT/ST
SX   Male
AG   <1M
CA   Transformed cell line
DT   Created: 05-10-23; Last updated: 19-12-24; Version: 4
//
RX   PubMed=18355723; DOI=10.1016/j.chembiol.2008.02.010; PMCID=PMC2683762;
RA   Yang W.S., Stockwell B.R.;
RT   "Synthetic lethal screening identifies compounds activating
RT   iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring
RT   cancer cells.";
RL   Chem. Biol. 15:234-245(2008).
//