Cellosaurus cell line HF2303 (CVCL

Cellosaurus HF2303 (CVCL_C8P8)

Cross-references
Cell line name	HF2303
Synonyms	HF-2303
Accession	CVCL_C8P8
Resource Identification Initiative	To cite this cell line use: HF2303 (RRID:CVCL_C8P8)
Comments	Group: Cancer stem cell line. Doubling time: 179 hours (PubMed=32064048). Miscellaneous: Established both as a cell culture and a neurosphere. Derived from site: In situ; Brain, left parietal lobe; UBERON=UBERON_0002802.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Unspecified (PubMed=32064048).
Disease	Gliosarcoma (NCIt: C3796) Gliosarcoma (ORDO: Orphanet_251576)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	62Y
Category	Cancer cell line
Publications	PubMed=27564115; DOI=10.18632/oncotarget.11589; PMCID=PMC5325344 Wilson T.J., Zamler D.B., Doherty R., Castro M.G., Lowenstein P.R. Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery tool. Oncotarget 7:63020-63041(2016) PubMed=32064048; DOI=10.18632/oncotarget.27457; PMCID=PMC6996910 Ye L.F., Reznik E., Korn J.M., Lin F., Yang G.-Z., Malesky K., Gao H., Loo A., Pagliarini R., Mikkelsen T., Lo D.C., deCarvalho A.C., Stockwell B.R. Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery. Oncotarget 11:443-451(2020)
Anatomy/cell type resources	BTO; BTO_0006543
Encyclopedic resources	Wikidata; Q123031641
Entry history
Entry creation	05-Oct-2023
Last entry update	19-Dec-2024
Version number	3