ID   K562/fes clone WS-5
AC   CVCL_C8IP
SY   K562/WS-5; WS-5
DR   Wikidata; Q123032788
RX   PubMed=2656706;
CC   Population: Caucasian.
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 12841; YES1.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C9110; Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0004 ! K-562
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 05-10-23; Last updated: 02-05-24; Version: 3
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RX   PubMed=2656706; DOI=10.1016/S0021-9258(18)81796-3;
RA   Yu G., Smithgall T.E., Glazer R.I.;
RT   "K562 leukemia cells transfected with the human c-fes gene acquire the
RT   ability to undergo myeloid differentiation.";
RL   J. Biol. Chem. 264:10276-10281(1989).
//