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Cellosaurus CHOL761h (CVCL_C8H6)

[Text version]
Cell line name CHOL761h
Synonyms CHO-L761h; CHOL76-1h
Accession CVCL_C8H6
Resource Identification Initiative To cite this cell line use: CHOL761h (RRID:CVCL_C8H6)
Comments Characteristics: Expresses a mutant form of the Ad5 E1A gene product under the control of a SV40 promoter. Allows maximal transactivation of constructs that are under the control of a hCMV-MIE promoter (Patent=US6653101; PubMed=1707522).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein (Note=With p.Glu126Gly = R1176E1A).
Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Children:
CVCL_C8HG (12.4F)CVCL_C8HH (DB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=1707522; DOI=10.1093/nar/19.2.319; PMCID=PMC333597
Cockett M.I., Bebbington C.R., Yarranton G.T.
The use of engineered E1A genes to transactivate the hCMV-MIE promoter in permanent CHO cell lines.
Nucleic Acids Res. 19:319-325(1991)

Patent=US6653101
Cockett M.I., Bebbington C.R., Yarranton G.T.
Recombinant DNA method and host cells.
Patent number US6653101, 25-Nov-2003

Cross-references
Encyclopedic resources Wikidata; Q123030925
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number4