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Cellosaurus SW620 M13KD (CVCL_C8D7)

[Text version]
Cell line name SW620 M13KD
Synonyms SW620 MUC13 KnockDown
Accession CVCL_C8D7
Resource Identification Initiative To cite this cell line use: SW620 M13KD (RRID:CVCL_C8D7)
Comments Population: Caucasian.
Doubling time: 20.5 hours (PubMed=24097071).
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:7511; MUC13.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0547 (SW620)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=24097071; DOI=10.1007/s00535-013-0885-z; PMCID=PMC3979492
Gupta B.K., Maher D.M., Ebeling M.C., Stephenson P.D., Puumala S.E., Koch M.R., Aburatani H., Jaggi M., Chauhan S.C.
Functions and regulation of MUC13 mucin in colon cancer cells.
J. Gastroenterol. 49:1378-1391(2014)

Cross-references
Encyclopedic resources Wikidata; Q123033582
Entry history
Entry creation29-Jun-2023
Last entry update19-Dec-2024
Version number4