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Cellosaurus HEKExpress (CVCL_C8CE)

[Text version]
Cell line name HEKExpress
Accession CVCL_C8CE
Resource Identification Initiative To cite this cell line use: HEKExpress (RRID:CVCL_C8CE)
Comments Group: Serum/protein free medium cell line.
Characteristics: Grows in suspension growth conditions in animal component-free media.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Caution: This cell line is incorrectly described as being derived from HEK293 (instead of HERK293T) in PubMed=30591923.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Children:
CVCL_C8CF (HEKzeroT)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages https://excellgene.com/technologies/
Publications

PubMed=30591923; DOI=10.1016/j.omtm.2018.11.004; PMCID=PMC6305802
Blessing D., Vachey G., Pythoud C., Rey M., Padrun V., Wurm F.M., Schneider B.L., Deglon N.
Scalable production of AAV vectors in orbitally shaken HEK293 cells.
Mol. Ther. Methods Clin. Dev. 13:14-26(2019)

PubMed=37232541; DOI=10.1002/bit.28414
Croissant C., Armitano J., Lazuech B., Svec D., Pugin C., Guesdon A., Bryan L., Castro A., Neuhaus L., Fonti G., Martinis J., Wurm M.J., Wurm F.M., Pino P.
A new T-antigen negative HEK293 cell line with improved AAV productivity.
Biotechnol. Bioeng. 120:1953-1960(2023)

Cross-references
Encyclopedic resources Wikidata; Q123031596
Entry history
Entry creation29-Jun-2023
Last entry update10-Sep-2024
Version number4