ID   HC50474
AC   CVCL_C8C7
SY   HC474
DR   Wikidata; Q123031529
RX   PubMed=3785179;
RX   PubMed=6526013;
RX   PubMed=8569793;
CC   Characteristics: Overproduces adenylate deaminase (PubMed=6526013).
CC   Selected for resistance to: ChEBI; CHEBI:16213; Coformycin.
CC   Selected for resistance to: ChEBI; CHEBI:28680; Cytarabine (Arabinosylcytosine; Ara-C).
CC   Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_C8C4 ! HC1047
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 29-06-23; Last updated: 30-01-24; Version: 2
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RX   PubMed=3785179; DOI=10.1128/mcb.6.5.1776-1781.1986; PMCID=PMC367706;
RA   Debatisse M., Hyrien O., Petit-Koskas E., Robert de Saint-Vincent B.,
RA   Buttin G.;
RT   "Segregation and rearrangement of coamplified genes in different
RT   lineages of mutant cells that overproduce adenylate deaminase.";
RL   Mol. Cell. Biol. 6:1776-1781(1986).
//
RX   PubMed=6526013; DOI=10.1002/j.1460-2075.1984.tb02268.x; PMCID=PMC557827;
RA   Debatisse M., Robert de Saint-Vincent B., Buttin G.;
RT   "Expression of several amplified genes in an adenylate-deaminase
RT   overproducing variant of Chinese hamster fibroblasts.";
RL   EMBO J. 3:3123-3127(1984).
//
RX   PubMed=8569793; DOI=10.1016/0027-5107(95)00153-0;
RA   Lunel-Orsini C., Buttin G., Robert de Saint-Vincent B.;
RT   "Reversion in Chinese hamster lines amplified at the AMPD2 locus:
RT   spontaneous and benzamide-stimulated gradual loss of amplified
RT   alleles of marker genes.";
RL   Mutat. Res. 349:63-75(1996).
//