Cellosaurus cell line LHON1-hiPSC1 (CVCL

Cross-references
Cell line name	LHON1-hiPSC1
Synonyms	LHON.1.H.iPSC.1; LHON-hiPSC1
Accession	CVCL_C880
Resource Identification Initiative	To cite this cell line use: LHON1-hiPSC1 (RRID:CVCL_C880)
Comments	From: Royan Institute; Theran; Iran. Population: Iranian. Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:7462; MT-ND6; Simple; p.Met64Val (m.14484T>C); ClinVar=VCV000009688; Zygosity=Unspecified (PubMed=22145677).
Disease	Leber hereditary optic atrophy (NCIt: C84808) Leber hereditary optic neuropathy (ORDO: Orphanet_104)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_C881 ! LHON1-hiPSC2 CVCL_C882 ! LHON1-hiPSC4 CVCL_C883 ! LHON1-hiPSC5
Sex of cell	Male
Age at sampling	48Y
Category	Induced pluripotent stem cell
Publications	PubMed=22145677; DOI=10.1089/scd.2011.0599 Zahabi A., Shahbazi E., Ahmadieh H., Hassani S.-N., Totonchi M., Taei A., Masoudi N.S., Ebrahimi M., Aghdami N., Seifinejad A., Mehrnejad F., Daftarian N., Salekdeh G.H., Baharvand H. A new efficient protocol for directed differentiation of retinal pigmented epithelial cells from normal and retinal disease induced pluripotent stem cells. Stem Cells Dev. 21:2262-2272(2012)
Cell line collections (Providers)	RSCB; RSCB0127
Encyclopedic resources	Wikidata; Q54902472
Entry history
Entry creation	22-Oct-2012
Last entry update	19-Dec-2024
Version number	13