Cellosaurus cell line MM548 (CVCL

Cellosaurus MM548 (CVCL_C848)

Cross-references
Cell line name	MM548
Synonyms	MM 548
Accession	CVCL_C848
Resource Identification Initiative	To cite this cell line use: MM548 (RRID:CVCL_C848)
Comments	Omics: CNV analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17363583). Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg99del; Zygosity=Unspecified (PubMed=9354451; PubMed=17363583).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=9354451 Castellano M., Pollock P.M., Walters M.K., Sparrow L.E., Down L.M., Gabrielli B.G., Parsons P.G., Hayward N.K. CDKN2A/p16 is inactivated in most melanoma cell lines. Cancer Res. 57:4868-4875(1997) PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152 Stark M.S., Hayward N.K. Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays. Cancer Res. 67:2632-2642(2007) PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x Johansson P., Pavey S., Hayward N.K. Confirmation of a BRAF mutation-associated gene expression signature in melanoma. Pigment Cell Res. 20:216-221(2007)
Cell line databases/resources	cancercelllines; CVCL_C848
Encyclopedic resources	Wikidata; Q54906167
Gene expression databases	GEO; GSM170978 GEO; GSM226728
Polymorphism and mutation databases	Cosmic; 928729 Progenetix; CVCL_C848
Entry history
Entry creation	22-Oct-2012
Last entry update	19-Dec-2024
Version number	16