ID   HTLA161
AC   CVCL_C834
SY   HTLA-161; HT-161; HT161; Ht161
DR   Cosmic; 931915
DR   Cosmic; 1070845
DR   Cosmic; 2816209
DR   Wikidata; Q54896574
RX   PubMed=2233717;
RX   PubMed=2253237;
RX   PubMed=3297309;
RX   PubMed=28196595;
WW   https://tcpaportal.org/mclp/
CC   Part of: MD Anderson Cell Lines Project.
CC   Sequence variation: Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (PubMed=2233717; PubMed=2253237).
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Derived from site: In situ; Bone, femur; UBERON=UBERON_0000981.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_W846 ! HTLA145
OI   CVCL_W847 ! HTLA195
SX   Sex unspecified
AG   Children
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 29-06-23; Version: 11
//
RX   PubMed=2233717; DOI=10.1128/mcb.10.11.5772-5781.1990;
RA   Diller L., Kassel J., Nelson C.E., Gryka M.A., Litwak G., Gebhardt M.,
RA   Bressac B., Ozturk M., Baker S.J., Vogelstein B., Friend S.H.;
RT   "p53 functions as a cell cycle control protein in osteosarcomas.";
RL   Mol. Cell. Biol. 10:5772-5781(1990).
//
RX   PubMed=2253237;
RA   Miller C.W., Aslo A., Tsay C., Slamon D.J., Ishizaki K., Toguchida J.,
RA   Yamamuro T., Lampkin B.C., Koeffler H.P.;
RT   "Frequency and structure of p53 rearrangements in human
RT   osteosarcoma.";
RL   Cancer Res. 50:7950-7954(1990).
//
RX   PubMed=3297309;
RA   Bogenmann E., Moghadam H., DeClerck Y.A., Mock A.F.;
RT   "c-myc amplification and expression in newly established human
RT   osteosarcoma cell lines.";
RL   Cancer Res. 47:3808-3814(1987).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//