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Cellosaurus U266R (CVCL_C828)

[Text version]
Cell line name U266R
Accession CVCL_C828
Resource Identification Initiative To cite this cell line use: U266R (RRID:CVCL_C828)
Comments Population: Caucasian.
Characteristics: Produces IgE lambda (from parent cell line).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Lys601Asn (c.1803A>T); ClinVar=VCV000376285; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; p.Gly141Asp (c.422G>A); ClinVar=VCV001491786; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 12033; TRAF3; Simple; p.Lys550Leufs*3 (c.1648_1649insT); Zygosity=Homozygous (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0566 (U266B1)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=8307198; DOI=10.1016/0014-5793(94)80287-4
Abramovich C., Ratovitski E., Lundgren E., Revel M.
Identification of mRNAs encoding two different soluble forms of the human interferon alpha-receptor.
FEBS Lett. 338:295-300(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C828
Encyclopedic resources Wikidata; Q54973647
Entry history
Entry creation22-Oct-2012
Last entry update10-Sep-2024
Version number18