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Cellosaurus LAPC4-AR (CVCL_C7X9)

[Text version]
Cell line name LAPC4-AR
Accession CVCL_C7X9
Resource Identification Initiative To cite this cell line use: LAPC4-AR (RRID:CVCL_C7X9)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; 644; AR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4744 (LAPC-4)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=14702632; DOI=10.1038/nm972
Chen C.D., Welsbie D.S., Tran C., Baek S.H., Chen R., Vessella R.L., Rosenfeld M.G., Sawyers C.L.
Molecular determinants of resistance to antiandrogen therapy.
Nat. Med. 10:33-39(2004)

Cross-references
Encyclopedic resources Wikidata; Q123032897
Entry history
Entry creation29-Jun-2023
Last entry update10-Sep-2024
Version number3