Cellosaurus cell line T105 (CVCL

Cellosaurus T105 (CVCL_C7VZ)

[Text version]

Cell line name

T105

Accession

CVCL_C7VZ

Resource Identification Initiative

To cite this cell line use: T105 (RRID:CVCL_C7VZ)

Comments

Doubling time: 29.64 +- 2.04 hours (Note=At 6 to 11 passages), 16.55 +- 0.15 hours (Note=At 60 to 62 passages) (PubMed=27723895).
Karyotypic information: Trisomy of chromosome 8 (PubMed=27723895).
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.

Sequence variations

Mutation; HGNC; HGNC:4379; GNA11; Simple; p.Gln209Leu (c.626A>T); ClinVar=VCV000376002; Zygosity=Unspecified (PubMed=27723895).

Disease

Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

Age unspecified

Category

Cancer cell line

STR profile

Source(s): PubMed=27723895

Markers:

Amelogenin	X
D1S1656	14,15
D2S441	12,15
D2S1338	19
D6S1043	11
D10S1248	14
D12S391	18,21
D19S433	17,18
D22S1045	16
TH01	7,9.3

Publications

PubMed=27723895; DOI=10.1167/iovs.16-19317
Mouriaux F., Zaniolo K., Bergeron M.-A., Weidmann C., de la Fouchardiere A., Fournier F., Droit A., Morcos M.W., Landreville S., Guerin S.L.
Effects of long-term serial passaging on the characteristics and properties of cell lines derived from uveal melanoma primary tumors.
Invest. Ophthalmol. Vis. Sci. 57:5288-5301(2016)

Cross-references

Encyclopedic resources

Wikidata; Q123033591

Entry history

Entry creation

29-Jun-2023

Last entry update

19-Dec-2024

Version number