ID   HME50-3
AC   CVCL_C7ST
DR   Wikidata; Q117704486
RX   PubMed=7799951;
RX   PubMed=17968319;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met133Thr (c.398T>C); ClinVar=VCV000012357; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
CC   Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
DI   NCIt; C3476; Li-Fraumeni syndrome
DI   ORDO; Orphanet_524; Li-Fraumeni syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C7T1 ! HME50
SX   Female
AG   31Y
CA   Finite cell line
DT   Created: 21-03-23; Last updated: 19-12-24; Version: 5
//
RX   PubMed=7799951; DOI=10.1128/mcb.15.1.425; PMCID=PMC231985;
RA   Shay J.W., Tomlinson G.E., Piatyszek M.A., Gollahon L.S.;
RT   "Spontaneous in vitro immortalization of breast epithelial cells from
RT   a patient with Li-Fraumeni syndrome.";
RL   Mol. Cell. Biol. 15:425-432(1995).
//
RX   PubMed=17968319; DOI=10.1038/sj.onc.1210886; PMCID=PMC3397201;
RA   Pearce V.P., Sherrell J., Lou Z.-J., Kopelovich L., Wright W.E.,
RA   Shay J.W.;
RT   "Immortalization of epithelial progenitor cells mediated by
RT   resveratrol.";
RL   Oncogene 27:2365-2374(2008).
//