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Cellosaurus MCF10A-EGFR1m-1 (CVCL_C7Q2)

[Text version]
Cell line name MCF10A-EGFR1m-1
Accession CVCL_C7Q2
Resource Identification Initiative To cite this cell line use: MCF10A-EGFR1m-1 (RRID:CVCL_C7Q2)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; 3236; EGFR (Note=With p.Leu858Arg).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0598 (MCF-10A)
Sex of cell Female
Age at sampling 36Y
Category Spontaneously immortalized cell line
Publications

PubMed=27840973; DOI=10.3892/or.2016.5227; PMCID=PMC5355725
Hoshi H., Hiyama G., Ishikawa K., Inageda K., Fujimoto J., Wakamatsu A., Togashi T., Kawamura Y., Takahashi N., Higa A., Goshima N., Semba K., Watanabe S., Takagi M.
Construction of a novel cell-based assay for the evaluation of anti-EGFR drug efficacy against EGFR mutation.
Oncol. Rep. 37:66-76(2017)

Cross-references
Cell line collections (Providers) CancerTools; 161168
Encyclopedic resources Wikidata; Q117704643
Entry history
Entry creation21-Mar-2023
Last entry update10-Sep-2024
Version number3