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Cellosaurus MKN1 CHRNB2 KO-1 (CVCL_C7NI)

[Text version]
Cell line name MKN1 CHRNB2 KO-1
Accession CVCL_C7NI
Resource Identification Initiative To cite this cell line use: MKN1 CHRNB2 KO-1 (RRID:CVCL_C7NI)
Comments Population: Japanese.
Knockout cell: Method=CRISPR/Cas9; HGNC; 1962; CHRNB2.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Disease Gastric adenosquamous carcinoma (NCIt: C5474)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1415 (MKN1)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=34331011; DOI=10.1038/s41388-021-01945-9
Kanda M., Shimizu D., Nakamura S., Sawaki K., Umeda S., Miwa T., Tanaka H., Inokawa Y., Hattori N., Hayashi M., Tanaka C., Nakayama G., Iguchi Y., Katsuno M., Kodera Y.
Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells.
Oncogene 40:5495-5504(2021)

Cross-references
Encyclopedic resources Wikidata; Q117704707
Entry history
Entry creation21-Mar-2023
Last entry update10-Sep-2024
Version number3