ID   A549-IR6
AC   CVCL_C7GT
DR   Wikidata; Q123030364
RX   PubMed=35976051;
CC   Population: Caucasian.
CC   Characteristics: Irradiated 6 times with 4 Gy and with at least a three-week interval between each two consecutive irradiations (PubMed=35976051).
CC   Doubling time: 28.23 hours (PubMed=35976051).
CC   Selected for resistance to: NCIt; C129640; Cobalt-60 gamma radiation.
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 21-03-23; Last updated: 30-01-24; Version: 3
//
RX   PubMed=35976051; DOI=10.1080/09553002.2022.2113837;
RA   Tsolou A., Koparanis D., Lamprou I., Giatromanolaki A.,
RA   Koukourakis M.I.;
RT   "Increased glucose influx and glycogenesis in lung cancer cells
RT   surviving after irradiation.";
RL   Int. J. Radiat. Biol. 99:692-701(2023).
//