ID   HAP1 FASTKD3-sKO
AC   CVCL_C6Y4
DR   Wikidata; Q117704465
RX   PubMed=34748562;
CC   Group: Haploid karyotype cell line.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 28758; FASTKD3.
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3174; Chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_Y019 ! HAP1
SX   Male
AG   40Y
CA   Cancer cell line
DT   Created: 21-03-23; Last updated: 29-06-23; Version: 2
//
RX   PubMed=34748562; DOI=10.1371/journal.pgen.1009873;
RA   Ohkubo A., Van Haute L., Rudler D.L., Stentenbach M., Steiner F.A.,
RA   Rackham O., Minczuk M., Filipovska A., Martinou J.-C.;
RT   "The FASTK family proteins fine-tune mitochondrial RNA processing.";
RL   PLoS Genet. 17:E1009873-E1009873(2021).
//