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Cellosaurus MHHi001-A-10 (CVCL_C6TV)

[Text version]
Cell line name MHHi001-A-10
Synonyms hiPSC Arclight/Neo; Arclight hiPSC
Accession CVCL_C6TV
Resource Identification Initiative To cite this cell line use: MHHi001-A-10 (RRID:CVCL_C6TV)
Comments From: Hannover Medical School, LEBAO (MHH); Hannover; Germany.
Population: Caucasian.
Characteristics: Using TALEN the voltage-sensor (GEVI) Arclight A242 and antibiotic resistance genes under the control of the cardiac-specific myosin heavy chain promoter (pCAG-Arclight-alphaMHC-Neo-PGKp-HygroR construct) were introduced in both alleles of the AAVS1 safe harbor locus (PubMed=36463634).
Genetic integration: Method=TALEN; Gene=Arclight A242 (Note=Fluorescent voltage sensor).
Genetic integration: Method=TALEN; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=TALEN; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_QX51 (MHHi001-A)
Sex of cell Female
Age at sampling <1D
Category Induced pluripotent stem cell
Publications

PubMed=36463634; DOI=10.1016/j.scr.2022.102981
Vivekanandan R., Szepes M., Ricci Signorini M.E., Kravchenko D., Kiefer J., Berger S., Fricke V., Gohring G., Gruh I.
Generation of human induced pluripotent stem cell line encoding for a genetically encoded voltage indicator Arclight A242.
Stem Cell Res. 66:102981-102981(2023)

Cross-references
Cell line databases/resources hPSCreg; MHHi001-A-10
Encyclopedic resources Wikidata; Q117704704
Entry history
Entry creation21-Mar-2023
Last entry update10-Sep-2024
Version number4