ID   USZ22-EMC2
AC   CVCL_C6MY
SY   UniversitatsSpital Zurich 2022-Extraskeletal Myxoid Chondrosarcoma 2
DR   Wikidata; Q116050752
RX   PubMed=36316541;
CC   Characteristics: Maintained as a sarco-sphere (PubMed=36316541).
CC   Doubling time: 6.05 days (PubMed=36316541).
CC   Sequence variation: Gene fusion; HGNC; HGNC:7982; NR4A3 + HGNC; HGNC:11547; TAF15; Name(s)=TAF15-NR4A3; Note=TAF15 exon 6 fused to NR4A3 exon 2 (PubMed=36316541).
CC   Sequence variation: Mutation; HGNC; HGNC:11114; KDM5C; Simple; c.1584-2A>T; Zygosity=Hemizygous; Note=Splice acceptor mutation (PubMed=36316541).
CC   Sequence variation: Mutation; HGNC; HGNC:13726; KMT2C; Simple; p.Glu1689fs*28 (c.5065delG); Zygosity=Unspecified (PubMed=36316541).
CC   Omics: DNA methylation analysis.
CC   Derived from site: In situ; Left thigh; UBERON=UBERON_0000376.
ST   Source(s): PubMed=36316541
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 11,14
ST   D16S539: 11,12
ST   D18S51: 12,13
ST   D21S11: 29
ST   D3S1358: 14,15
ST   D5S818: 10,12
ST   D7S820: 10
ST   D8S1179: 10,13
ST   FGA: 22
ST   Penta D: 12,13
ST   Penta E: 12,13
ST   TH01: 7,9.3
ST   TPOX: 8,9
ST   vWA: 15,16
DI   NCIt; C27502; Extraskeletal myxoid chondrosarcoma
DI   ORDO; Orphanet_209916; Extraskeletal myxoid chondrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 15-12-22; Last updated: 19-12-24; Version: 5
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RX   PubMed=36316541; DOI=10.1007/s13577-022-00818-x; PMCID=PMC9813045;
RA   Bangerter J.L., Harnisch K.J., Chen Y.-J., Hagedorn C., Planas-Paz L.,
RA   Pauli C.;
RT   "Establishment, characterization and functional testing of two novel
RT   ex vivo extraskeletal myxoid chondrosarcoma (EMC) cell models.";
RL   Hum. Cell 36:446-455(2023).
//