ID   PCNY1
AC   CVCL_C6LS
SY   PCNY-1
DR   Wikidata; Q116050113
RX   PubMed=21565982;
RX   PubMed=32133047;
CC   Sequence variation: Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Heterozygous (PubMed=21565982).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gly (c.742C>G); ClinVar=VCV000376652; Zygosity=Heterozygous (PubMed=21565982; PubMed=32133047).
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 15-12-22; Last updated: 19-12-24; Version: 4
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RX   PubMed=21565982; DOI=10.1158/1078-0432.CCR-10-1820; PMCID=PMC3131419;
RA   Nardiello T., Jungbluth A.A., Mei A.H.-C., Di Liberto M., Huang X.-G.,
RA   Dabrowski A., Andrade V.C.C., Wasserstrum R., Ely S., Niesvizky R.,
RA   Pearse R., Coleman M., Jayabalan D.S., Bhardwaj N., Old L.J.,
RA   Chen-Kiang S., Cho H.J.;
RT   "MAGE-A inhibits apoptosis in proliferating myeloma cells through
RT   repression of Bax and maintenance of survivin.";
RL   Clin. Cancer Res. 17:4309-4319(2011).
//
RX   PubMed=32133047; DOI=10.18632/oncotarget.27488; PMCID=PMC7041939;
RA   Mei A.H.-C., Tung K., Han J., Perumal D., Lagana A., Keats J.J.,
RA   Auclair D., Chari A., Jagannath S., Parekh S., Cho H.J.;
RT   "MAGE-A inhibit apoptosis and promote proliferation in multiple
RT   myeloma through regulation of BIM and p21(Cip1).";
RL   Oncotarget 11:727-739(2020).
//