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Cellosaurus HROG17-CIITA (CVCL_C6JX)

[Text version]
Cell line name HROG17-CIITA
Accession CVCL_C6JX
Resource Identification Initiative To cite this cell line use: HROG17-CIITA (RRID:CVCL_C6JX)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7067; CIITA.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Omics: Proteomics; HLA class I peptidome.
Omics: Proteomics; HLA class II peptidome.
Derived from site: In situ; Brain, left parieto-occipital lobe.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg130Ter (c.388C>T); ClinVar=VCV000007819; Zygosity=Unspecified (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4U45 (HROG17)
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
Publications

PubMed=33592498; DOI=10.1074/mcp.RA120.002201; PMCID=PMC8724627
Forlani G., Michaux J., Pak H., Huber F., Lauret Marie-Joseph E., Ramia E., Stevenson B.J., Linnebacher M., Accolla R.S., Bassani-Sternberg M.
CIITA-transduced glioblastoma cells uncover a rich repertoire of clinically relevant tumor-associated HLA-II antigens.
Mol. Cell. Proteomics 20:100032.1-100032.21(2021)

Cross-references
Encyclopedic resources Wikidata; Q116049505
Proteomic databases PRIDE; PXD020079
Entry history
Entry creation15-Dec-2022
Last entry update10-Apr-2025
Version number6