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Cellosaurus GSC-326/ALDH1A3-KO.3.5 (CVCL_C6J9)

[Text version]
Cell line name GSC-326/ALDH1A3-KO.3.5
Accession CVCL_C6J9
Resource Identification Initiative To cite this cell line use: GSC-326/ALDH1A3-KO.3.5 (RRID:CVCL_C6J9)
Comments Group: Cancer stem cell line.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:409; ALDH1A3.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Cell type: Mesenchymal stem cell; CL=CL_0000134.
Disease Malignant glioma (NCIt: C4822)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C6IR (GSC-326)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=34934174; DOI=10.1038/s42003-021-02949-7; PMCID=PMC8692581
Li J.-F., Garavaglia S., Ye Z.-F., Moretti A., Belyaeva O.V., Beiser A., Ibrahim M., Wilk A., McClellan S., Klyuyeva A.V., Goggans K.R., Kedishvili N.Y., Salter E.A., Wierzbicki A., Migaud M.E., Mullett S.J., Yates N.A., Camacho C.J., Rizzi M., Sobol R.W.
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells.
Commun. Biol. 4:1420.1-1420.16(2021)

Cross-references
Encyclopedic resources Wikidata; Q116049095
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number4